Principal Biostatistician

Principal Biostatistician | Global CRO | UK | Home Based | Permanent |

Due to continued global growth, we are supporting a leading full-service CRO with the appointment of Principal Biostatisticians to join their expanding UK remote team.

This organisation is recognised for its statistical and data management expertise, high-quality deliverables, superior customer service, and flexible, collaborative approach to clinical research. Working with some of the industry’s most innovative drugs, biologics, and medical devices in development today, this is an exciting opportunity to join a growing and highly respected global CRO.

With an established international presence across North America and Asia, the organisation continues to experience exceptional growth and success within the clinical research market.

What you will be doing:

• Lead and oversee clinical trial programs/projects across one or multiple clients, providing day-to-day technical and operational leadership to project teams
• Provide statistical oversight across study design, sample size estimation, statistical analysis planning, statistical modeling, analysis, and reporting
• Serve as the lead biostatistician within cross-functional teams, contributing strategically to drug development and commercialization activities
• Provide statistical input into protocol development, clinical trial design, and research proposals
• Write and review Statistical Analysis Plans (SAPs), Statistical Reports, and statistical sections of Clinical Study Reports
• Perform hands-on statistical analysis and modeling while maintaining expertise in emerging methodologies and regulatory expectations
• Review and validate statistical outputs including tables, listings, figures, and ADaM dataset specifications to ensure quality and accuracy
• Support regulatory submissions and interact with regulatory agencies, ensuring compliance with CDISC and applicable industry standards
• Collaborate closely with Data Management teams, contributing to eCRFs, data validation specifications, Data Review Plans, and Data Management Plans
• Mentor, coach, and provide technical guidance to Biostatisticians and Statistical Programmers
• Contribute to continuous improvement initiatives, resource planning, metrics, and organisational growth activities including interviewing and evaluating candidates
• Support publication activities including abstracts, manuscripts, posters, and presentations

What you will need:

• PhD in Statistics, Mathematical Analysis, Biostatistics, or related field with 7+ years of relevant industry experience OR Master’s degree with 10+ years of relevant experience
• Strong clinical trial statistics experience within a CRO or pharmaceutical environment
• Advanced proficiency in SAS
• Solid understanding of clinical trial methodology, statistical modelling, and regulatory requirements
• Experience authoring and reviewing SAPs, Statistical Reports, and Clinical Study Reports
• Strong knowledge of CDISC standards including ADaM datasets
• Proven ability to lead projects and provide technical oversight across clinical development programs
• Excellent communication and stakeholder management skills
• Ability to mentor and develop junior team members
• Strong organisational skills with the ability to manage multiple priorities and deadlines
• High attention to detail and commitment to quality deliverables

What’s in it for you:

• Join a globally recognised CRO experiencing continued international growth
• Work on innovative and complex clinical development programs with leading pharmaceutical and biotechnology clients
• Fully home-based opportunity within the UK
• Collaborative, customer-focused, and entrepreneurial working environment
• Excellent long-term career development and leadership opportunities
• Competitive salary and benefits package

What to do next:
If this opportunity is of interest, please apply now with your CV as the organisation is looking to welcome experienced Principal Biostatisticians to the team as soon as possible.

Not what you’re looking for?
Please contact Jo Fornaciari at jo@warmanobrien.com for a confidential discussion regarding other opportunities across the UK and Europe.